AdipoGen VEGF-C rat rec His
Protein. Rat VEGF-C 127aa is fused at the C-terminus to a His-tag. Source Sf9 cells. Lyophilized. Purity >90% SDS-PAGE. VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 KDR/FLK1 and VEGFR-3 FLT4 receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.